Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 19/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860507 | 0.85 | MALT1 (0.53) | MALT1SMN1; SMN2 | |
| SCHEMBL2850226 | 0.84 | MALT1 (0.56) | MALT1 | |
| SCHEMBL10364566 | 0.83 | KDM4E (0.52) | MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL2854006 | 0.82 | NPC1 (0.54) | MALT1KDM4EGAASMN1; SMN2 | |
| SCHEMBL30147861 | 0.81 | MALT1 (0.73) | MALT1 | |
| SCHEMBL21604889 | 0.81 | MALT1 (0.73) | MALT1 | |
| SCHEMBL2854611 | 0.81 | TRPV1 (0.41) | MALT1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1335647 | 0.80 | MAPT (0.68) | MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL29419571 | 0.80 | MAPT (0.68) | MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL2852442 | 0.80 | MALT1 (0.56) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |