Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854476 | 0.84 | MALT1 (0.56) | MALT1 | |
| SCHEMBL2852553 | 0.83 | MALT1 (0.40) | MALT1 | |
| SCHEMBL2852124 | 0.82 | TRPC1 (0.51) | MALT1 | |
| SCHEMBL15187958 | 0.82 | KEAP1 (0.50) | MALT1 | |
| SCHEMBL2295633 | 0.81 | MAPT (0.60) | MALT1 | |
| SCHEMBL2855599 | 0.80 | MALT1 (0.57) | MALT1 | |
| SCHEMBL2855512 | 0.80 | MALT1 (0.55) | MALT1 | |
| SCHEMBL2850508 | 0.78 | CCR1 (0.48) | — | |
| SCHEMBL2860507 | 0.78 | MALT1 (0.53) | MALT1 | |
| SCHEMBL2850397 | 0.77 | MALT1 (0.57) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |