Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911006 | 1.00 | AGER (0.47) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL3370759 | 0.85 | AGER (0.55) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL5436734 | 0.83 | AGER (0.55) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL5431901 | 0.83 | AGER (0.55) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL1700010 | 0.81 | MC4R (0.49) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL17506917 | 0.81 | MC4R (0.49) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL736913 | 0.79 | AGER (0.50) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL736914 | 0.79 | AGER (0.50) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL17157336 | 0.78 | AGER (0.50) | AGERMTNR1ACTSDCHRM2CHRM3 | |
| SCHEMBL17157513 | 0.78 | AGER (0.50) | AGERMTNR1ACTSDCHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137586-B | Novel imidazo [4,5-c ] quinoline and imidazo [4,5-c ] [1,5] naphthyridine derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2021-04-13 | — | — | CN | disclosed |