Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734216 | 0.87 | RIPK1 (0.40) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28314759 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28315694 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28316460 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28315770 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28314617 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL28315837 | 0.85 | RIPK1 (0.39) | GRNSORT1RIPK1GAAMEN1 | |
| SCHEMBL9392724 | 0.79 | CHRM1 (0.41) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL7637165 | 0.79 | CA1 (0.37) | GRNSORT1GAACA2 | |
| SCHEMBL15383712 | 0.78 | ACACB (0.33) | GAAACACBACACATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661639-A | Synthesis method of 4-acetylbutyrate compound | 浙江工业大学 | 2021-04-16 | — | — | CN | disclosed |