Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.58 |
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28544838 | 1.00 | HRH4 (0.58) | HRH4HRH3IRAK4HRH2DDB1 | |
| SCHEMBL22895365 | 0.87 | HRH3 (0.47) | HRH4HRH3IRAK4HRH2DDB1 | |
| Trifluoroacetic Acid SCHEMBL28545442 | 0.86 | HRH4 (0.60) | HRH4HRH3IRAK4HRH2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL28547917 | 0.86 | HRH4 (0.54) | HRH4HRH3IRAK4 | |
| Trifluoroacetic Acid SCHEMBL28551360 | 0.86 | HRH4 (0.54) | HRH4HRH3IRAK4HRH2 | |
| Trifluoroacetic Acid SCHEMBL28547919 | 0.86 | HRH4 (0.54) | HRH4HRH3IRAK4 | |
| Trifluoroacetic Acid SCHEMBL28545444 | 0.86 | HRH4 (0.60) | HRH4HRH3IRAK4HRH2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL28551359 | 0.86 | HRH4 (0.54) | HRH4HRH3IRAK4HRH2 | |
| Trifluoroacetic Acid SCHEMBL28549700 | 0.81 | HRH4 (0.56) | HRH4HRH3IRAK4DDB1CRBN | |
| Trifluoroacetic Acid SCHEMBL28549697 | 0.81 | HRH4 (0.56) | HRH4HRH3IRAK4DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |