Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28549697

O=C(O)C(F)(F)F.c1cc(N[C@@H]2CCNC2)ncc1C1CC1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.56
HRH3 Q9Y5N1 2/20 0.56
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
IRAK4 Q9NWZ3 6/20 0.40
HCAR3 P49019 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28549700 1.00 HRH4 (0.56) HRH4HRH3DDB1CRBNIRAK4
SCHEMBL22895707 0.89 DDB1 (0.53) HRH4HRH3DDB1CRBNIRAK4
Trifluoroacetic Acid SCHEMBL28549612 0.86 HRH4 (0.51) HRH4HRH3IRAK4
Trifluoroacetic Acid SCHEMBL28549613 0.86 HRH4 (0.51) HRH4HRH3IRAK4
Trifluoroacetic Acid SCHEMBL28545444 0.84 HRH4 (0.60) HRH4HRH3IRAK4HCAR3
Trifluoroacetic Acid SCHEMBL28545442 0.84 HRH4 (0.60) HRH4HRH3IRAK4HCAR3
Trifluoroacetic Acid SCHEMBL28544840 0.81 HRH4 (0.58) HRH4HRH3DDB1CRBNIRAK4
Trifluoroacetic Acid SCHEMBL28544838 0.81 HRH4 (0.58) HRH4HRH3DDB1CRBNIRAK4
Trifluoroacetic Acid SCHEMBL28551360 0.80 HRH4 (0.54) HRH4HRH3IRAK4
Trifluoroacetic Acid SCHEMBL28547917 0.80 HRH4 (0.54) HRH4HRH3IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638373-A Cyclin-dependent kinase inhibitors 金耐特生物制药公司 2021-04-09 CN disclosed