SCHEMBL28544862

SCHEMBL28544862

CC(C)CC#N.S=C(S)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 5/20 0.38
CTSS P25774 5/20 0.38
CTSB P07858 4/20 0.38
CTSK P43235 3/20 0.38
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
PBRM1 Q86U86 1/20 0.33
POLB P06746 1/20 0.33
XBP1 P17861 1/20 0.33
MAOB P27338 1/20 0.33
CYP19A1 P11511 1/20 0.33
HSP90AA1 P07900 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25192767 0.82 MAPT (0.38) CTSLCTSSCTSBCTSKALDH1A1
SCHEMBL28215676 0.79 CA12 (0.44) ALDH1A1MAPTHPGDPOLBHSP90AA1
SCHEMBL28911205 0.79 CTSL (0.36) CTSLCTSSCTSBCTSKALDH1A1
SCHEMBL28688796 0.76 CTSL (0.37) CTSLCTSSCTSBCTSKALDH1A1
SCHEMBL35105 0.74
Benzene SCHEMBL9276657 0.74 TSHR (0.38) CTSLCTSSCTSBCTSKALDH1A1
Benzene SCHEMBL28151406 0.74 CA12 (0.52) ALDH1A1MAPTHPGDPOLBHSP90AA1
SCHEMBL28330913 0.74 CA12 (0.52) ALDH1A1MAPTHPGDPOLBHSP90AA1
SCHEMBL2791417 0.72 MAOB (0.36) CTSLCTSSCTSBCTSKALDH1A1
SCHEMBL161152 0.72 NR4A2 (0.38) CTSLCTSSCTSBCTSKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375450-A Method for preparing super-hydrophobic coating by polymerizing water-based RAFT miniemulsion 浙江理工大学 2021-02-19 CN claimed