Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354504 | 0.79 | SLC7A5 (0.41) | PARP10PARP15SIRT2FFAR1MAOB | |
| SCHEMBL28351071 | 0.77 | EPHX2 (0.46) | PARP10PARP15SIRT2PPARGPPARD | |
| SCHEMBL5703994 | 0.77 | PARP10 (0.47) | PARP10LMNAMEN1KMT2APRSS1 | |
| SCHEMBL16502888 | 0.77 | MEN1 (0.54) | PARP10LMNAMEN1KMT2APRSS1 | |
| SCHEMBL17801666 | 0.77 | KMT2A (0.52) | PARP10PARP15MEN1KMT2APARP14 | |
| SCHEMBL2821420 | 0.75 | CA12 (0.42) | CA1MAOB | |
| SCHEMBL18260811 | 0.75 | MEN1 (0.45) | LMNAMEN1KMT2APPARD | |
| SCHEMBL29045152 | 0.73 | KDM4E (0.61) | PARP10LMNAMEN1KMT2APPARG | |
| SCHEMBL28554950 | 0.73 | MAP2K1 (0.40) | LMNA | |
| SCHEMBL26586977 | 0.72 | FFAR1 (0.33) | PPARGPPARDFFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024466-A | Tetra-substituted olefin compound and use thereof | 卫材 R&D 管理有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-107847498-B | Tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2021-04-13 | — | — | CN | disclosed |