SCHEMBL17801666

SCHEMBL17801666

NC(=O)Oc1ccc(I)c(F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
KIF11 P52732 1/20 0.42
PARP10 Q53GL7 7/20 0.34
PARP15 Q460N3 4/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PRSS1 P07477 1/20 0.32
TMPRSS15 P98073 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CPS1 P31327 1/20 0.32
TLR8 Q9NR97 1/20 0.32
PARP14 Q460N5 3/20 0.31
ALDH1A1 P00352 1/20 0.31
PARP16 Q8N5Y8 1/20 0.31
PARP11 Q9NR21 1/20 0.31
PARP4 Q9UKK3 1/20 0.31
CHRNA3 P32297 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30063441 0.82 MEN1 (0.57) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL5265818 0.82 MEN1 (0.57) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL27511537 0.79 MEN1 (0.53) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL4311410 0.79 MEN1 (0.53) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL29178740 0.79 MEN1 (0.47) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL440172 0.78 MEN1 (0.52) KMT2AMEN1KIF11PARP10PARP15
SCHEMBL5260935 0.78 MEN1 (0.52) KMT2AMEN1KIF11CHRNA3
SCHEMBL28615804 0.78 KMT2A (0.52) KMT2AMEN1KIF11PARP10NPC1
SCHEMBL27565314 0.78 KMT2A (0.52) KMT2AMEN1KIF11NPC1RAB9A
SCHEMBL28544920 0.77 PARP10 (0.38) KMT2AMEN1PARP10PARP15PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164975-A Quaternary ammonium salt oxazolidinone derivative and pharmaceutically acceptable salt thereof, preparation method and application 中国医学科学院医药生物技术研究所 2024-06-11 CN disclosed
CN-108976222-B Heterocyclic ring-containing biaryl oxazolidinone compound and preparation method thereof 沈阳药科大学 2021-09-03 CN disclosed
WO-2016088102-A1 PROCESSES FOR THE PREPARATION OF TEDIZOLID PHOSPHATE AND ITS INTERMEDIATES SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2016-06-09 WO disclosed