SCHEMBL28544960

SCHEMBL28544960

C1=CCC(Oc2cccc3ccccc23)=C1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 7/20 0.41
SLC6A4 P31645 2/20 0.41
KCNA3 P22001 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
PGR P06401 1/20 0.39
GAA P10253 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39
HTR1D P28221 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HRH1 P35367 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL10636467 0.75 HTR1B (0.50) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL29577853 0.74 HTR1B (0.54) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL442767 0.74 HTR1B (0.54) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
Lithium SCHEMBL6571336 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL27339322 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
Methane SCHEMBL10959030 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL27559989 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL7457103 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
Phosphine SCHEMBL28264511 0.72 HTR1B (0.52) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10
SCHEMBL5501740 0.72 SLC6A4 (0.41) HTR1BSLC6A4KCNA3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661785-A Naphthyloxy single metallocene transition metal compound, catalyst composition containing naphthoxy single metallocene transition metal compound and application of catalyst composition 中国石油化工股份有限公司 2021-04-16 CN claimed
CN-112661785-B Naphthyloxy single metallocene transition metal compound, catalyst composition containing naphthoxy single metallocene transition metal compound and application of catalyst composition 中国石油化工股份有限公司 2022-10-21 CN disclosed