Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22521076 | 0.77 | MAPT (0.40) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28545006 | 0.72 | ALDH1A1 (0.35) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24429224 | 0.67 | MAPT (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27664204 | 0.66 | CNR2 (0.32) | LMNA | |
| SCHEMBL2099625 | 0.65 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6608600 | 0.65 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12259007 | 0.64 | KAT2B (0.51) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18255879 | 0.64 | MAPT (0.38) | MAPTKDM4EALDH1A1 | |
| SCHEMBL3724833 | 0.63 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6605048 | 0.63 | HTT (0.55) | MAPTKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709323-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-11-20 | — | — | CN | disclosed |