Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17422251 | 0.99 | GPR119 (0.49) | HPGDGPR119ALDH1A1TSHRRAB9A | |
| SCHEMBL17431867 | 0.86 | GPR119 (0.52) | GPR119ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL21122527 | 0.85 | HPGD (0.54) | HPGDALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL20584215 | 0.84 | GPR119 (0.52) | GPR119ALDH1A1LMNAMAPTHTT | |
| SCHEMBL17422296 | 0.84 | HPGD (0.54) | HPGDALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL18879761 | 0.84 | HPGD (0.58) | HPGDALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL18879721 | 0.83 | HPGD (0.56) | HPGDALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL17422241 | 0.83 | HPGD (0.52) | HPGDALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL17432245 | 0.81 | GPR119 (0.51) | GPR119ALDH1A1LMNAMAPTHTT | |
| SCHEMBL17432219 | 0.81 | GPR119 (0.53) | GPR119HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473504-B | Novel dihydropyranopyrimidinone derivatives and uses thereof | ST制药株式会社 | 2021-04-16 | — | — | CN | disclosed |