Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856997 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTMAPK1RAB9AGAA | |
| SCHEMBL2861123 | 0.82 | NPC1 (0.47) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL2854719 | 0.81 | MAPT (0.55) | ALDH1A1MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL2853491 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1RAB9AGAA | |
| SCHEMBL2858605 | 0.80 | MAPT (0.53) | ALDH1A1MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL2850541 | 0.80 | MAPT (0.58) | ALDH1A1MAPTMAPK1RAB9AGAA | |
| SCHEMBL2857911 | 0.80 | MAPT (0.47) | ALDH1A1MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL2858440 | 0.79 | MAPT (0.70) | ALDH1A1MAPTMAPK1RAB9AGAA | |
| SCHEMBL2853414 | 0.79 | MAPK14 (0.55) | ALDH1A1MAPTMAPK1RAB9AGAA | |
| SCHEMBL2856278 | 0.79 | MAPT (0.56) | ALDH1A1MAPTMAPK1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |