Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747524 | 0.84 | RAB9A (0.48) | MAOBKMT2AGLAKDM4EMAPT | |
| SCHEMBL7747520 | 0.84 | RAB9A (0.48) | MAOBKMT2AGLAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5703014 | 0.83 | RAB9A (0.47) | MAOBKMT2AGLAKDM4EMAPT | |
| SCHEMBL13673707 | 0.83 | MAOB (0.45) | MAOBKMT2AGLAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5703009 | 0.83 | RAB9A (0.47) | MAOBKMT2AGLAKDM4EMAPT | |
| SCHEMBL29522846 | 0.80 | MAOB (1.00) | MAOBKMT2AKDM4EGAAL3MBTL1 | |
| SCHEMBL7650941 | 0.80 | MAOB (1.00) | MAOBKMT2AKDM4EGAAL3MBTL1 | |
| SCHEMBL7650937 | 0.80 | MAOB (1.00) | MAOBKMT2AKDM4EGAAL3MBTL1 | |
| SCHEMBL19449728 | 0.80 | RAB9A (0.47) | MAOBKMT2AKDM4EMAPTPOLB | |
| SCHEMBL18746291 | 0.76 | MAOB (0.74) | MAOBKMT2AKDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645897-B | Thiazole derivative and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2022-05-24 | — | — | CN | disclosed |
| CN-112645897-A | Thiazole derivative and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-04-13 | — | — | CN | disclosed |