Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.55 |
| ▸ | CCNK | O75909 | 1/20 | 0.53 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292271 | 1.00 | USP30 (0.55) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL22895515 | 1.00 | USP30 (0.55) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL22895710 | 0.88 | CCNK (0.52) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL24179474 | 0.88 | USP30 (0.51) | USP30PIK3CDALDH1A1BTKMAPT | |
| SCHEMBL23292337 | 0.88 | CCNK (0.52) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL28547880 | 0.88 | CCNK (0.52) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL25851878 | 0.88 | USP30 (0.51) | USP30PIK3CDALDH1A1BTKMAPT | |
| SCHEMBL23292281 | 0.87 | USP30 (0.54) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL22895552 | 0.87 | USP30 (0.54) | USP30CCNKCDK12PIK3CDALDH1A1 | |
| SCHEMBL28911208 | 0.87 | USP30 (0.54) | USP30CCNKCDK12PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |