Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292337 | 1.00 | CCNK (0.52) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL22895710 | 1.00 | CCNK (0.52) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL22895690 | 0.93 | CCNK (0.54) | CCNKCDK12USP30PIK3CDBTK | |
| SCHEMBL23292436 | 0.93 | CCNK (0.54) | CCNKCDK12USP30PIK3CDBTK | |
| SCHEMBL28546438 | 0.93 | CCNK (0.54) | CCNKCDK12USP30PIK3CDBTK | |
| SCHEMBL22895515 | 0.88 | USP30 (0.55) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL28545458 | 0.88 | USP30 (0.55) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL23292271 | 0.88 | USP30 (0.55) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL23292407 | 0.86 | USP30 (0.53) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL22895670 | 0.86 | USP30 (0.53) | CCNKCDK12USP30ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |