Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.75 |
| ▸ | KLK1 | P06870 | 4/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854366 | 0.94 | KLKB1 (0.80) | KLKB1KLK1 | |
| SCHEMBL2850615 | 0.89 | KLKB1 (0.73) | KLKB1KLK1 | |
| SCHEMBL15145224 | 0.86 | KLKB1 (0.63) | KLKB1KLK1 | |
| SCHEMBL1981938 | 0.86 | KLKB1 (1.00) | KLKB1KLK1 | |
| SCHEMBL25910310 | 0.86 | KLKB1 (0.80) | KLKB1KLK1 | |
| SCHEMBL22878729 | 0.86 | KLKB1 (0.69) | KLKB1KLK1 | |
| SCHEMBL15145189 | 0.85 | KLKB1 (0.71) | KLKB1KLK1 | |
| SCHEMBL22878728 | 0.85 | KLKB1 (0.78) | KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL1985633 | 0.85 | KLKB1 (0.98) | KLKB1KLK1 | |
| SCHEMBL2858761 | 0.84 | LMNA (0.76) | KLKB1SCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |