Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493417 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL17011976 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL22592522 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL14696629 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13568053 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL36444 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL10080567 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL1889993 | 0.77 | — | — | |
| SCHEMBL12005962 | 0.77 | — | — | |
| SCHEMBL17493419 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003348-B | Siloxane bridged ladder-shaped polysiloxane, preparation method and application thereof | 长兴（中国）投资有限公司 | 2021-02-23 | — | — | CN | disclosed |