SCHEMBL28545815

SCHEMBL28545815

O=CNOCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.46
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.33
APP P05067 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1695523 1.00 MEN1 (0.50) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL4466095 0.85
Triethylene Glycol SCHEMBL5411901 0.75 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL12140167 0.73 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL14190546 0.73 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL28734839 0.72 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL29248396 0.72 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL28734864 0.72 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL399171 0.72 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL29053656 0.72 TSHR (0.67) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112626180-A DNA hybridization enhancing solution and preparation method and application thereof 北京思尔成生物技术有限公司 2021-04-09 CN claimed
CN-112626180-A DNA hybridization enhancing solution and preparation method and application thereof 北京思尔成生物技术有限公司 2021-04-09 CN disclosed