⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545815 | 0.85 | MEN1 (0.50) | — | |
| SCHEMBL1695523 | 0.85 | MEN1 (0.50) | — | |
| SCHEMBL5309892 | 0.84 | — | — | |
| SCHEMBL841743 | 0.72 | — | — | |
| SCHEMBL16622619 | 0.72 | — | — | |
| SCHEMBL8374688 | 0.72 | — | — | |
| Formic Acid SCHEMBL1836113 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL2995999 | 0.72 | — | — | |
| SCHEMBL5650162 | 0.69 | — | — | |
| SCHEMBL8582243 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049591-A1 | Inhibitors of MAPK/Erk Kinase | KALYPSYS, INC. | 2007-03-01 | — | — | US | claimed |
| EP-0020156-A2 | Cap-sensitive powdered explosive composition | DYNO INDUSTRIER A/S (NO) | 1980-12-10 | — | — | EP | claimed |
| CN-105051005-B | Cyclopropylamine compound and use thereof | 武田药品工业株式会社 | 2017-06-13 | — | — | CN | disclosed |
| CN-103842332-B | Cyclopropylamine compound | 武田药品工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-103304356-B | The synthetic method of azanol | BEIJING LAVIANA PHARMATECH CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103842332-A | Cyclopropaneamine compound | TAKAEDA CHEMICAL IND LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-102015705-B | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2013-11-13 | — | — | CN | disclosed |
| CN-103304356-A | Hydroxylamine synthesis method | BEIJING LAVIANA PHARMATECH CO LTD | 2013-09-18 | — | — | CN | disclosed |
| CN-102015705-A | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-04-13 | — | — | CN | disclosed |
| EP-2032663-A2 | METHOD FOR GRAFTING BIOACTIVE POLYMERS ON PROSTHETIC MATERIALS | Universite Paris 13 (FR) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007141460-A2 | METHOD FOR GRAFTING BIOACTIVE POLYMERS ON PROSTHETIC MATERIALS | UNIVERSITE PARIS 13 (FR) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007025090-A2 | HETEROBICYCLIC AND - TRICYCLIC INHIBITORS OF MAPK/ERK KINASE | KALYPSYS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070049591-A1 | Inhibitors of MAPK/Erk Kinase | KALYPSYS, INC. | 2007-03-01 | — | — | US | disclosed |
| EP-0862650-A1 | IN SITU HYBRIDIZATION TO DETECT SPECIFIC NUCLEIC ACID SEQUENCES IN EUCARYOTIC SAMPLES | DAKO A/S (DK) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997018325-A1 | IN SITU HYBRIDIZATION TO DETECT SPECIFIC NUCLEIC ACID SEQUENCES IN EUCARYOTIC SAMPLES | DAKO A/S (DK) | 1997-05-22 | — | — | WO | disclosed |
| US-4975433-A | DRUG DELIVERY FOR TREATING SKIN DISORDERS | UNIVERSITY OF FLORIDA (US) | 1990-12-04 | — | — | US | disclosed |
| US-4845081-A | PRODRUGS, URACILS | UNIVERSITY OF FLORIDA (US) | 1989-07-04 | — | — | US | disclosed |