SCHEMBL28546150

SCHEMBL28546150

[HH].c1ccc([Si](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 5/20 0.33
TDP1 Q9NUW8 5/20 0.33
ALOX12 P18054 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CA7 P43166 1/20 0.33
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 3/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27879268 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL38901 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
Benzene SCHEMBL28223369 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
Hydrochloric Acid SCHEMBL6905007 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL21838773 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Phosphine SCHEMBL28254857 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Fluoride SCHEMBL28572273 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Phosphine SCHEMBL29078666 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL27804862 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Fluoride SCHEMBL27639926 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108697587-B Dental composition 登特斯普伊德特雷有限公司 2022-06-17 CN disclosed
CN-109152701-B Dental composition 登特斯普伊德特雷有限公司 2022-04-08 CN disclosed
CN-108135782-B Dental composition 登特斯普伊德特雷有限公司 2022-03-22 CN disclosed
CN-114031615-A Hydroxy-substituted pyridine oxazoline ligands and application thereof in hydrohalogenation reaction of olefin 中国科学院上海有机化学研究所 2022-02-11 CN disclosed
CN-108135781-B Dental composition 登特斯普伊德特雷有限公司 2021-04-16 CN disclosed