Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1117737 | 0.83 | TSHR (0.55) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL2470229 | 0.81 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL51153 | 0.81 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL2128784 | 0.81 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL15021274 | 0.79 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL11444701 | 0.79 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL11444625 | 0.79 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL28546168 | 0.78 | TSHR (0.44) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL7263832 | 0.77 | TSHR (0.48) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL5178293 | 0.77 | TSHR (0.48) | TSHRALDH1A1IDO1AGXTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382967-B | Carbazole sulfonamide derivative or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2021-02-19 | — | — | CN | disclosed |