Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2700294 | 0.90 | MAPT (0.70) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL29617508 | 0.90 | MAPT (0.70) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL28539974 | 0.85 | KCNMA1 (0.56) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL18341074 | 0.82 | KCNMA1 (0.56) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL3713378 | 0.80 | MAPT (0.65) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL24362462 | 0.79 | MAPT (0.68) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL20415476 | 0.79 | MAPT (0.64) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL18341346 | 0.79 | MAPT (0.64) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL12834027 | 0.79 | MEN1 (0.71) | KCNMA1NPC1RAB9ALMNAMAPT | |
| SCHEMBL29617511 | 0.79 | MEN1 (0.71) | KCNMA1NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434770-B | P-nitroaniline compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-04-13 | — | — | CN | disclosed |