Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701303 | 1.00 | KDM4E (0.54) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29701312 | 0.94 | TACR1 (0.48) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29701310 | 0.91 | KDM4E (0.58) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL28548565 | 0.87 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL528960 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL28546877 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29701308 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29701301 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL598940 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29431877 | 0.84 | KDM4E (0.55) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971037-A | Compositions comprising N-acetyl or N-acyl amino acids for the treatment of atopy or pruritis | 斯特姆德公司 | 2020-11-20 | — | — | CN | disclosed |