Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 17/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541415 | 0.86 | CHRM2 (0.78) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28527169 | 0.86 | CHRM2 (0.78) | CHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL28537600 | 0.84 | CHRM3 (0.75) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28644233 | 0.84 | CHRM3 (0.87) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28541398 | 0.81 | CHRM2 (0.69) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28713024 | 0.81 | CHRM2 (0.69) | CHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL28691392 | 0.79 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28711696 | 0.78 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28538595 | 0.77 | CHRM2 (0.74) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL28538632 | 0.77 | CHRM2 (0.74) | CHRM2CHRM1CHRM3CHRM5CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107080747-B | Glucosylceramide synthase inhibitors | 建新公司 | 2021-02-26 | — | — | CN | disclosed |