Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.87 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.87 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.87 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541398 | 0.87 | CHRM2 (0.69) | CHRM3CHRM2CHRM1CYP2D6CHRM4 | |
| SCHEMBL28713024 | 0.87 | CHRM2 (0.69) | CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL28527169 | 0.86 | CHRM2 (0.78) | CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL28541415 | 0.86 | CHRM2 (0.78) | CHRM3CHRM2CHRM1CHRNA7CYP2D6 | |
| SCHEMBL28706755 | 0.84 | CHRM2 (0.66) | CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL28537600 | 0.84 | CHRM3 (0.75) | CHRM3CHRM2CHRM1CYP2D6CHRM4 | |
| SCHEMBL28547261 | 0.84 | CHRM2 (0.75) | CHRM3CHRM2CHRM1CYP2D6CHRM4 | |
| SCHEMBL28703595 | 0.83 | CHRM2 (0.63) | CHRM3CHRM2CHRM1CYP2D6CHRM4 | |
| SCHEMBL28696817 | 0.83 | CHRM2 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12615810 | 0.81 | CHRM2 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427038-A | Methods of treating nervous system symptoms associated with lysosomal storage diseases | 建新公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-114040762-A | Treatment of ciliary disease using inhibitors of glucosylceramide synthase (GCS) | 建新公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-113710249-A | Methods for treating symptoms and disorders associated with lysosomal storage disorders | 建新公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113645969-A | Methods for treating symptoms and disorders associated with lysosomal storage disorders | 建新公司 | 2021-11-12 | — | — | CN | disclosed |