SCHEMBL285473

SCHEMBL285473

CCCCc1cccc2c1ccc1c3ccccc3ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.50
BCHE P06276 1/20 0.46
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
GAA P10253 5/20 0.42
KDM4E B2RXH2 4/20 0.42
NPC1 O15118 4/20 0.42
HTT P42858 4/20 0.42
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GLA P06280 1/20 0.42
RCE1 Q9Y256 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801506 1.00 HPRT1 (0.50) HPRT1BCHEALDH1A1TDP1CYP2A6
SCHEMBL1023164 0.95 HPRT1 (0.48) HPRT1BCHEALDH1A1TDP1CYP2A6
SCHEMBL19433085 0.95 HPRT1 (0.48) HPRT1BCHEALDH1A1TDP1CYP2A6
SCHEMBL16666257 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL9764124 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL28452662 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL9621111 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL2577637 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL28339808 0.93 LIPG (0.49) HPRT1BCHEALDH1A1TDP1GAA
SCHEMBL598995 0.89 HPRT1 (0.54) HPRT1ALDH1A1TDP1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427531-A1 DEUTERATED COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. du Pont de Nemours and Company (US) 2012-03-14 EP disclosed
WO-2010128996-A1 DEUTERATED COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-11 WO disclosed