Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725734 | 0.77 | PRCP (0.50) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL28995850 | 0.76 | ADRA1A (0.49) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27737121 | 0.74 | ADRA1A (0.51) | GID4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5023257 | 0.73 | RECQL (0.59) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL7702387 | 0.73 | RECQL (0.59) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL7698338 | 0.73 | RECQL (0.59) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL7433439 | 0.72 | PRCP (0.49) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL1597975 | 0.72 | KDM1A (0.69) | PRCPGAARECQLGID4TSHR | |
| SCHEMBL7704168 | 0.72 | PRCP (0.61) | PRCPGAARECQLGID4MAPT | |
| SCHEMBL7704163 | 0.72 | PRCP (0.61) | PRCPGAARECQLGID4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566894-A | Potent inhibitors of D-amino acid oxidase (DAAO) and uses thereof | 心悦生医股份有限公司 | 2021-03-26 | — | — | CN | disclosed |