Phenyl Propionic Acid

Phenyl Propionic Acid

SCHEMBL28547712

CCCCCCOc1cccc(CCC(=O)OC)c1.O=C(O)CCc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.58
PPARG P37231 2/20 0.58
CNR1 P21554 1/20 0.55
CNR2 P34972 1/20 0.55
FFAR1 O14842 4/20 0.55
PLA2G4B P0C869 2/20 0.55
CYP2D6 P10635 2/20 0.54
P2RY10 O00398 4/20 0.53
KCNH2 Q12809 1/20 0.52
GPR174 Q9BXC1 3/20 0.52
GPR34 Q9UPC5 1/20 0.52
CYSLTR2 Q9NS75 1/20 0.51
CYSLTR1 Q9Y271 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Propionic Acid SCHEMBL28554549 0.95 FFAR1 (0.60) PPARAPPARGFFAR1PLA2G4BCYP2D6
SCHEMBL17320239 0.93 CNR1 (0.61) PPARAPPARGCNR1CNR2PLA2G4B
Phenyl Propionic Acid SCHEMBL28543757 0.92 LMNA (0.59) PPARAPPARGFFAR1
SCHEMBL25456542 0.91 PPARA (0.69) PPARAPPARGCNR1CNR2FFAR1
SCHEMBL17345292 0.91 PPARA (0.69) PPARAPPARGCNR1CNR2FFAR1
SCHEMBL12255204 0.88 CYP2D6 (0.59) PPARAPPARGCNR1CNR2PLA2G4B
Phenyl Propionic Acid SCHEMBL28541991 0.87 FFAR1 (0.57) PPARAPPARGFFAR1
SCHEMBL17413765 0.86 FFAR1 (0.66) PPARAPPARGCNR1CNR2FFAR1
SCHEMBL1206101 0.85 PPARA (0.64) PPARAPPARGFFAR1PLA2G4BCYP2D6
SCHEMBL17413763 0.84 FFAR1 (0.69) PPARAPPARGFFAR1PLA2G4BCYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438238-B Synthetic method of dihydrocinnamate compound 陕西师范大学 2021-04-13 CN disclosed