Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556442 | 0.87 | CYP2D6 (0.40) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL8578383 | 0.83 | CYP2D6 (0.42) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL5873561 | 0.83 | GLO1 (0.40) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL8576108 | 0.83 | GLO1 (0.40) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL9653714 | 0.83 | GLO1 (0.40) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL38654747 | 0.81 | NPSR1 (0.39) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL10959515 | 0.79 | GLO1 (0.42) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL10959518 | 0.79 | GLO1 (0.42) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL29188692 | 0.77 | GLO1 (0.41) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL134789 | 0.72 | GLO1 (0.50) | GLO1CYP2D6CYP2C19NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503657-B | Synthesis method of 4-dihydrocarbyloxyphosphono-2-methyl-2-butenoic acid alkyl ester | 浙江新和成股份有限公司 | 2021-03-02 | — | — | CN | disclosed |