Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390365 | 0.80 | PLD1 (0.38) | SMN1; SMN2PLD1CRBNKDM4EALDH1A1 | |
| SCHEMBL1383463 | 0.75 | ALKBH2 (0.41) | SMN1; SMN2CRBNKDM4EALDH1A1 | |
| SCHEMBL2513039 | 0.74 | HPGD (0.47) | SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL1370074 | 0.74 | PLK4 (0.38) | SMN1; SMN2CRBNKDM4EALDH1A1MAPT | |
| SCHEMBL28536215 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2CD274PDCD1PLD1KDM4E | |
| SCHEMBL28545863 | 0.72 | HTT (0.43) | SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL28013191 | 0.72 | KDM4E (0.44) | SMN1; SMN2CRBNKDM4EALDH1A1 | |
| SCHEMBL2096767 | 0.70 | PLD1 (0.44) | SMN1; SMN2PLD1CRBNKDM4EALDH1A1 | |
| SCHEMBL30565007 | 0.70 | PLD1 (0.44) | SMN1; SMN2PLD1CRBNKDM4EALDH1A1 | |
| SCHEMBL1140766 | 0.70 | PLD1 (0.47) | SMN1; SMN2CD274PDCD1PLD1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-B | Method for synthesizing pyrido [1,2-a ] indole-6 (1H) -ketone compound by manganese catalysis | 陕西师范大学 | 2021-04-09 | — | — | CN | disclosed |