SCHEMBL28547838

SCHEMBL28547838

CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)c1nc(Cc2ccccc2)no1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRC P12931 7/20 0.61
P4HB P07237 4/20 0.60
GAA P10253 3/20 0.60
MAPT P10636 2/20 0.60
POLB P06746 1/20 0.60
NPSR1 Q6W5P4 1/20 0.57
SSTR3 P32745 1/20 0.57
TSHR P16473 1/20 0.56
ZAP70 P43403 1/20 0.55
CTSL P07711 1/20 0.52
CTSS P25774 1/20 0.52
CTSK P43235 1/20 0.52
ACE P12821 1/20 0.52
TACR1 P25103 2/20 0.50
KLK7 P49862 1/20 0.49
CYP3A4 P08684 1/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30241815 1.00 SRC (0.61) SRCP4HBGAAMAPTPOLB
SCHEMBL26611316 1.00 SRC (0.61) SRCP4HBGAAMAPTPOLB
SCHEMBL26611805 0.95 SRC (0.60) SRCP4HBGAAMAPTPOLB
SCHEMBL28546615 0.95 SRC (0.60) SRCP4HBGAAMAPTPOLB
SCHEMBL30241818 0.95 SRC (0.60) SRCP4HBGAAMAPTPOLB
SCHEMBL21062751 0.87 SRC (0.64) SRCZAP70CTSL
SCHEMBL21062749 0.87 SRC (0.64) SRCZAP70CTSL
SCHEMBL4115544 0.87 P4HB (0.64) SRCP4HBGAAMAPTPOLB
SCHEMBL25472768 0.84 SRC (0.57) SRCP4HBGAAMAPTPOLB
SCHEMBL30241796 0.84 SRC (0.57) SRCP4HBGAAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111954539-B Mitochondrial targeting peptides 隐形生物治疗公司 2024-06-21 CN disclosed
CN-117624286-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-03-01 CN disclosed
CN-111954539-A Mitochondrial targeting peptides 隐形生物治疗公司 2020-11-17 CN disclosed