SCHEMBL28548520

SCHEMBL28548520

CCc1ccc(C(=O)Oc2ccccc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.50
RAB9A P51151 3/20 0.50
CASP3 P42574 3/20 0.50
SENP8 Q96LD8 3/20 0.50
SENP7 Q9BQF6 3/20 0.50
SENP6 Q9GZR1 3/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
SRD5A2 P31213 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 2/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADORA3 P0DMS8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7425995 0.87 MAPT (0.48) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL28550468 0.85 SRD5A2 (0.46) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL4358292 0.82 HPGD (0.51) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL4351853 0.82 MAPT (0.54) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL8422589 0.82 MAPT (0.53) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL4363059 0.81 HPGD (0.58) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL29187222 0.81 MEN1 (0.58) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL28371497 0.81 KMT2A (0.60) HSD17B10RAB9ACASP3SENP8SENP7
SCHEMBL28056878 0.80 MAOB (0.58) RAB9ASRD5A2SMN1; SMN2KMT2AALDH1A1
SCHEMBL28343739 0.79 KMT2A (0.56) HSD17B10RAB9ACASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed