SCHEMBL4351853

SCHEMBL4351853

Cc1cc(C(=O)Oc2ccccc2)ccc1C(=O)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.54
ALDH1A1 P00352 3/20 0.54
POLB P06746 1/20 0.53
NSD2 O96028 1/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
HPGD P15428 3/20 0.51
ALOX15 P16050 2/20 0.51
HSD17B10 Q99714 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 2/20 0.51
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
CHRM1 P11229 1/20 0.51
TBXA2R P21731 1/20 0.51
SLC6A2 P23975 1/20 0.51
PDE4A P27815 1/20 0.51
ADRA1A P35348 1/20 0.51
KDR P35968 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11584095 0.88 MAPT (0.53) MAPTALDH1A1POLBNSD2KMT2A
SCHEMBL16493491 0.88 KMT2A (0.50) MAPTALDH1A1POLBKMT2AMEN1
SCHEMBL8423740 0.88 MAPT (0.66) MAPTALDH1A1POLBNSD2KMT2A
SCHEMBL8422589 0.86 MAPT (0.53) MAPTALDH1A1POLBKMT2AMEN1
SCHEMBL4358292 0.86 HPGD (0.51) MAPTALDH1A1POLBNSD2KMT2A
SCHEMBL347341 0.86 MAPT (0.57) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL4363059 0.85 HPGD (0.58) MAPTALDH1A1POLBNSD2KMT2A
SCHEMBL29187222 0.85 MEN1 (0.58) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL26040490 0.84 MAPT (0.47) MAPTALDH1A1POLBKMT2AMEN1
SCHEMBL13005791 0.83 MAPT (0.55) MAPTALDH1A1POLBNSD2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
US-4065431-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid diols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed