Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582142 | 0.94 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL29180240 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL28579528 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL28582163 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL11141747 | 0.85 | CA12 (0.42) | ALDH1A1KMT2AMEN1CYP2C9TSHR | |
| SCHEMBL20501797 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL17815986 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL21822983 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL28618342 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 | |
| SCHEMBL29180255 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1CYP2C9TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-112601743-A | Flavone compounds for treating and preventing hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2021-04-02 | — | — | CN | disclosed |