Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548543 | 1.00 | GAA (0.37) | GAAMAPTRAB9ARECQLALDH1A1 | |
| SCHEMBL1694342 | 0.88 | GAA (0.44) | GAAMAPTRAB9ARECQLALDH1A1 | |
| SCHEMBL3993142 | 0.82 | ALDH1A1 (0.44) | GAAMAPTRAB9AALDH1A1POLB | |
| SCHEMBL3388901 | 0.82 | GAA (0.41) | GAAMAPTRAB9AALDH1A1POLB | |
| SCHEMBL27006521 | 0.81 | GAA (0.42) | GAAMAPTRAB9ARECQLALDH1A1 | |
| SCHEMBL27130827 | 0.81 | GAA (0.42) | GAAMAPTRAB9ARECQLALDH1A1 | |
| SCHEMBL24512542 | 0.80 | ALDH1A1 (0.46) | GAAMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1739339 | 0.80 | ALDH1A1 (0.46) | GAAMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6058686 | 0.78 | MAPT (0.50) | MAPTRECQLALDH1A1POLB | |
| SCHEMBL15566435 | 0.78 | GAA (0.37) | GAAMAPTRAB9ARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424198-A | Thiadiazine derivatives | 吉瑞工厂 | 2021-02-26 | — | — | CN | disclosed |