Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.52 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551433 | 0.86 | GPR119 (0.48) | GPR119CKS1BSKP1SKP2PTPN11 | |
| SCHEMBL21550983 | 0.85 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2PTPN11 | |
| SCHEMBL29891027 | 0.85 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2PTPN11 | |
| SCHEMBL28538439 | 0.81 | HRH4 (0.45) | KIT | |
| SCHEMBL21551682 | 0.81 | GPR119 (0.54) | GPR119 | |
| SCHEMBL30931826 | 0.78 | GPR119 (0.53) | GPR119CKS1BSKP1SKP2ADK | |
| SCHEMBL29891789 | 0.78 | GPR119 (0.53) | GPR119CKS1BSKP1SKP2ADK | |
| SCHEMBL21551124 | 0.78 | GPR119 (0.53) | GPR119CKS1BSKP1SKP2ADK | |
| SCHEMBL21159159 | 0.77 | GPR119 (0.60) | GPR119CKS1BSKP1SKP2PTPN11 | |
| SCHEMBL21551056 | 0.77 | GPR119 (0.48) | GPR119CKS1BSKP1SKP2ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |