SCHEMBL28548772

SCHEMBL28548772

CCCOC(=O)[C@@H]1CC=CC[C@@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.47
MAPK1 P28482 1/20 0.46
PPM1B O75688 1/20 0.45
PTPN1 P18031 1/20 0.45
PPP1CC P36873 1/20 0.45
TSHR P16473 2/20 0.41
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 3/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.37
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519041 1.00 POLB (0.47) POLBMAPK1PPM1BPTPN1PPP1CC
SCHEMBL28410422 0.93 PPM1B (0.42) POLBMAPK1PPM1BPTPN1PPP1CC
SCHEMBL1169671 0.93 PPM1B (0.42) POLBMAPK1PPM1BPTPN1PPP1CC
SCHEMBL28890578 0.93 PPM1B (0.42) POLBMAPK1PPM1BPTPN1PPP1CC
SCHEMBL28553312 0.90 MAPK1 (0.53) POLBMAPK1TSHRALDH1A1
SCHEMBL5517151 0.90 MAPK1 (0.53) POLBMAPK1TSHRALDH1A1
SCHEMBL28564418 0.88 POLB (0.55) POLBMAPK1TSHRALDH1A1
SCHEMBL5514840 0.87 POLB (0.54) POLBMAPK1TSHRALDH1A1LMNA
SCHEMBL5512498 0.87 POLB (0.54) POLBMAPK1TSHRALDH1A1LMNA
SCHEMBL5518200 0.87 POLB (0.54) POLBMAPK1TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661881-B Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2022-12-13 CN claimed
CN-112661882-B Application of cyclohexene-1,2-dicarboxylic acid ester compound 中国石油化工股份有限公司 2022-10-21 CN claimed
CN-112661883-B Solid catalyst component for preparing polyolefin, catalyst system and application thereof 中国石油化工股份有限公司 2022-10-21 CN claimed
CN-112661881-A Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-04-16 CN claimed
CN-112661883-A Solid catalyst component for preparing polyolefin, catalyst system and application thereof 中国石油化工股份有限公司 2021-04-16 CN claimed
CN-112661882-A Application of cyclohexene-1, 2-dicarboxylate compound 中国石油化工股份有限公司 2021-04-16 CN claimed
CN-112661881-B Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2022-12-13 CN disclosed
CN-112661882-B Application of cyclohexene-1,2-dicarboxylic acid ester compound 中国石油化工股份有限公司 2022-10-21 CN disclosed
CN-112661883-B Solid catalyst component for preparing polyolefin, catalyst system and application thereof 中国石油化工股份有限公司 2022-10-21 CN disclosed
CN-112661881-A Olefin polymerization catalyst component, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-04-16 CN disclosed
CN-112661882-A Application of cyclohexene-1, 2-dicarboxylate compound 中国石油化工股份有限公司 2021-04-16 CN disclosed
CN-112661883-A Solid catalyst component for preparing polyolefin, catalyst system and application thereof 中国石油化工股份有限公司 2021-04-16 CN disclosed