Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.67 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570119 | 0.92 | MAOB (0.63) | MAOBSCN3APARP15PARP10PARP14 | |
| SCHEMBL2772725 | 0.80 | FFAR1 (0.61) | MAOBRAB9AFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL2556909 | 0.79 | TAAR1 (0.56) | SMN1; SMN2 | |
| SCHEMBL29373563 | 0.79 | TAAR1 (0.56) | SMN1; SMN2 | |
| SCHEMBL11464931 | 0.78 | FFAR1 (0.59) | MAOBRAB9AFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL2168244 | 0.78 | TSHR (0.60) | MAOBSCN3APARP15PARP10PARP14 | |
| SCHEMBL28570332 | 0.78 | FFAR1 (0.71) | MAOBFFAR1FFAR4 | |
| SCHEMBL28558238 | 0.78 | MAOB (0.68) | MAOBSCN3APARP15PARP10PARP14 | |
| SCHEMBL23642694 | 0.77 | MAOB (0.67) | MAOBSCN3APARP15PARP10PARP14 | |
| SCHEMBL4229059 | 0.76 | MAOB (0.71) | MAOBSCN3APARP15PARP10PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112716927-B | Alpha-amino amide compound and preparation method and application thereof | 复旦大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-112716927-A | Alpha-amino amide compound and preparation method and application thereof | 复旦大学 | 2021-04-30 | — | — | CN | disclosed |