SCHEMBL2556909

SCHEMBL2556909

O=CCCc1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.56
IDO1 P14902 2/20 0.47
AOC3 Q16853 1/20 0.46
MPO P05164 3/20 0.44
LMNA P02545 1/20 0.42
DAO P14920 3/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373563 1.00 TAAR1 (0.56) TAAR1IDO1AOC3MPOLMNA
SCHEMBL96466 0.88 TAAR1 (0.52) TAAR1IDO1AOC3MPOLMNA
SCHEMBL7348409 0.84 TAAR1 (0.39) TAAR1IDO1AOC3MPOLMNA
SCHEMBL28607303 0.84 ADH1B (0.36) TAAR1MPOLMNACYP2D6ALDH1A1
SCHEMBL4846506 0.83 TAAR1 (0.38) TAAR1IDO1MPOLMNAHPGD
SCHEMBL28548848 0.79 MAOB (0.67) SMN1; SMN2
SCHEMBL7563209 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPOLMNA
SCHEMBL436798 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPOLMNA
SCHEMBL12478612 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPOLMNA
SCHEMBL28344566 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPOLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115627118-B Ball valve casting and processing technology thereof 温州市海格阀门有限公司 2024-03-19 CN claimed
CN-115627118-A Ball valve casting and machining process thereof 温州市海格阀门有限公司 2023-01-20 CN claimed
CN-106083686-B The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound 苏州大学 2019-01-22 CN claimed
CN-105801550-A Novel benzopyran kinase modulators 理森制药股份公司 2016-07-27 CN claimed
US-5140009-A Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders TAP PHARMACEUTICALS, INC. (US) 1992-08-18 US claimed
EP-0417454-A2 Reduced size LHRH analogs ABBOTT LABORATORIES (US) 1991-03-20 EP claimed
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof ALECTOS THERAPEUTICS 1NC (CA) 2026-04-28 US disclosed
EP-3966199-B1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2026-03-18 EP disclosed
CN-115627118-B Ball valve casting and processing technology thereof 温州市海格阀门有限公司 2024-03-19 CN disclosed
CN-115627118-B Ball valve casting and processing technology thereof 温州市海格阀门有限公司 2024-03-19 CN disclosed
CN-116332873-A Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2023-06-27 CN disclosed
EP-3177601-B1 TLR-INDEPENDENT SMALL MOLECULE ADJUVANTS SCRIPPS RESEARCH INST (US) 2023-03-01 EP disclosed
CN-115627118-A Ball valve casting and machining process thereof 温州市海格阀门有限公司 2023-01-20 CN disclosed
EP-0771196-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-05-07 EP disclosed
EP-0767790-A1 CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1997-04-16 EP disclosed
WO-1996007405-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-03-14 WO disclosed
EP-0695290-A1 N-FLUOROSULPHONIMIDES, METHOD OF PREPARING THEM AND THEIR USE AS FLUORINATION AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1996-02-07 EP disclosed
WO-1995035296-A1 CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-12-28 WO disclosed
WO-1994024098-A1 Ξ-FLUOROSULPHONIMIDES, METHOD OF PREPARING THEM AND THEIR USE AS FLUORINATION AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed
US-4415572-A CARDIOTONIC AND INOTROPIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1983-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof GBA1, GBA2, MAN2B1 TAAR1 3573/4885IDO1 2074/4885AOC3 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.