Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544051 | 0.81 | IRAK4 (0.42) | IRAK4IRAK1MAPTALDH1A1POLB | |
| SCHEMBL15910992 | 0.81 | NQO2 (0.43) | NQO2MAPTALDH1A1POLBCYP3A4 | |
| SCHEMBL30506082 | 0.81 | PABPC1 (0.41) | IRAK4NQO2MAPTALDH1A1POLB | |
| SCHEMBL28551229 | 0.79 | IRAK4 (0.40) | IRAK4IRAK1FLT3 | |
| SCHEMBL31324373 | 0.78 | IRAK4 (0.36) | IRAK4IRAK1MAPTFLT3CHEK1 | |
| SCHEMBL31217375 | 0.78 | NQO2 (0.41) | NQO2MAPTALDH1A1POLBCYP3A4 | |
| SCHEMBL15910493 | 0.76 | MAPT (0.51) | NQO2MAPTALDH1A1POLBCYP3A4 | |
| SCHEMBL25941155 | 0.76 | IRAK4 (0.42) | IRAK4IRAK1MAPTALDH1A1POLB | |
| SCHEMBL15910682 | 0.76 | NQO2 (0.43) | NQO2MAPTALDH1A1POLBCYP3A4 | |
| SCHEMBL25592539 | 0.72 | NQO2 (0.36) | NQO2MAPTALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737451-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003988-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |
| CN-112654604-B | 7-substituted indazole derivative, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112654604-A | 7-substituted indazole derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2021-04-13 | — | — | CN | disclosed |