Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557357 | 0.90 | AURKB (0.49) | ADORA1ADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL28022116 | 0.89 | ADORA1 (0.47) | ADORA1ADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL28021591 | 0.88 | AURKB (0.51) | ADORA1ADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL28553059 | 0.86 | ADORA1 (0.45) | ADORA1ADORA3ADORA2AMEN1KMT2A | |
| SCHEMBL28022051 | 0.86 | HRH4 (0.41) | SMN1; SMN2AURKAAURKBMAPTPOLB | |
| SCHEMBL28570220 | 0.86 | BPTF (0.38) | MEN1KMT2ASMN1; SMN2AURKAAURKB | |
| SCHEMBL28565368 | 0.85 | AURKB (0.44) | MEN1KMT2ASMN1; SMN2NPC1AURKA | |
| SCHEMBL28022063 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28549341 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2ANPC1AURKBALDH1A1 | |
| SCHEMBL2200635 | 0.81 | AURKB (0.61) | ADORA1ADORA3ADORA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112755193-A | Method of treating malignancies with anti-tyrosine kinase inhibitors using dianhydrogalactitol or a derivative thereof | 德玛医药 | 2021-05-07 | — | — | CN | disclosed |