SCHEMBL28548969

SCHEMBL28548969

Clc1cc(Cl)c(OOOc2c(Cl)cc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
TSHR P16473 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP3A4 P08684 3/20 0.41
RECQL P46063 3/20 0.41
HPGD P15428 3/20 0.36
AHR P35869 1/20 0.36
KMT2A Q03164 4/20 0.35
TP53 P04637 2/20 0.35
CYP1A2 P05177 3/20 0.33
CYP2D6 P10635 3/20 0.33
MEN1 O00255 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
CYP2C9 P11712 1/20 0.33
PPARG P37231 1/20 0.32
MAPT P10636 3/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28548967 0.88 ALDH1A1 (0.50) ALDH1A1CA1CA2CA9TSHR
SCHEMBL9320811 0.75 ALDH1A1 (0.50) ALDH1A1CA1CA2CA9TSHR
SCHEMBL4550664 0.73 ALDH1A1 (0.47) ALDH1A1CA1CA2CA9TSHR
SCHEMBL1044921 0.71 ALDH1A1 (0.45) ALDH1A1CA1CA2CA9TSHR
SCHEMBL54507 0.71 KMT2A (0.47) ALDH1A1CA1CA2CA9TSHR
SCHEMBL9483013 0.69 ALDH1A1 (0.43) ALDH1A1CA1CA2CA9TSHR
SCHEMBL9622239 0.67 PLAU (0.61) ALDH1A1CA1CA2CA9TSHR
SCHEMBL317719 0.67 CA1 (0.46) ALDH1A1CA1CA2CA9TSHR
SCHEMBL10871679 0.67 CA1 (0.41) ALDH1A1CA1CA2CA9TSHR
SCHEMBL11376213 0.67 CA1 (0.41) ALDH1A1CA1CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108421541-B Preparation method and application of Zn-carbide-based MOFs extraction coating 南京大学 2021-04-27 CN disclosed