Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | CCR3 | P51677 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199005 | 0.89 | OPRL1 (0.62) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL8804780 | 0.85 | OPRL1 (0.67) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL653329 | 0.85 | OPRL1 (0.67) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL1411499 | 0.83 | OPRL1 (1.00) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL7406058 | 0.83 | OPRL1 (0.65) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL1366704 | 0.83 | OPRL1 (0.65) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL1990088 | 0.82 | OPRL1 (0.63) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL7401723 | 0.82 | POLB (0.66) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL8913063 | 0.82 | OPRL1 (0.58) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL1147211 | 0.82 | OPRL1 (0.63) | OPRL1POLBSIGMAR1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112543756-A | Substituted oxazolidinones for the treatment of mammalian infections | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |