Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 7/20 | 0.38 |
| ▸ | KDR | P35968 | 9/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707252 | 1.00 | FLT3 (0.38) | FLT3KDRKMONPC1RAB9A | |
| SCHEMBL29707229 | 0.83 | FLT3 (0.38) | FLT3KDRKMOFGFR3CDK7 | |
| SCHEMBL28554374 | 0.83 | FLT3 (0.38) | FLT3KDRKMOFGFR3CDK7 | |
| SCHEMBL29707264 | 0.78 | SMN1; SMN2 (0.33) | FLT3KDRKMOFGFR3CDK7 | |
| SCHEMBL28571878 | 0.78 | SMN1; SMN2 (0.33) | FLT3KDRKMOFGFR3CDK7 | |
| SCHEMBL28554534 | 0.77 | KMO (0.36) | FLT3KMOCDK7CLK4CDC7 | |
| SCHEMBL29707244 | 0.77 | KMO (0.36) | FLT3KMOCDK7CLK4CDC7 | |
| SCHEMBL20903396 | 0.77 | KDR (0.46) | FLT3KDRFGFR3 | |
| SCHEMBL28554980 | 0.73 | SMN1; SMN2 (0.38) | KMONPC1RAB9A | |
| SCHEMBL29707230 | 0.73 | SMN1; SMN2 (0.38) | KMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574211-B | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112574211-A | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |