Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21197797 | 0.76 | — | — | |
| SCHEMBL11569552 | 0.74 | — | — | |
| SCHEMBL10073428 | 0.74 | CHRM3 (0.44) | TSHR | |
| SCHEMBL23466938 | 0.73 | TDP1 (0.36) | TSHRHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9623341 | 0.71 | PTGS1 (0.36) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL23466917 | 0.70 | KDM4E (0.37) | TSHRHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL10399368 | 0.70 | — | — | |
| SCHEMBL9266718 | 0.69 | — | — | |
| SCHEMBL9445764 | 0.68 | — | — | |
| SCHEMBL11450034 | 0.68 | GSTP1 (0.33) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232314-B | Synthesis method of polysubstituted 2-cyclopentenyl ethyl acetate compound | 河南理工大学 | 2021-04-06 | — | — | CN | claimed |