Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550702 | 0.74 | TSHR (0.37) | TSHR | |
| SCHEMBL10073430 | 0.72 | — | — | |
| SCHEMBL12728724 | 0.72 | — | — | |
| SCHEMBL27563816 | 0.68 | CHRM3 (0.49) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL9499237 | 0.65 | — | — | |
| SCHEMBL20314870 | 0.65 | TSHR (0.60) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL6665184 | 0.64 | CHRM3 (0.45) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL7910143 | 0.62 | PTPN1 (0.35) | — | |
| SCHEMBL3233925 | 0.62 | TSHR (0.35) | TSHR | |
| Bromide SCHEMBL9629760 | 0.61 | CHRM3 (0.53) | CHRM3TSHRSLC6A1SLC6A13BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088402-A1 | SYNTHESIS OF CONOLIDINE AND DISCOVERY OF A POTENT NON-OPIOID ANALGESIC FOR PAIN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-06-28 | — | — | WO | disclosed |