SCHEMBL2855093

SCHEMBL2855093

C=CN1CCN(c2ccccc2)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
LMNA P02545 2/20 0.42
CHRNA7 P36544 2/20 0.42
SIGMAR1 Q99720 2/20 0.42
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
ADRB1 P08588 1/20 0.42
HTR3A P46098 1/20 0.42
HTR3D Q70Z44 1/20 0.42
HTR3C Q8WXA8 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DRD4 P21917 1/20 0.41
KCNH2 Q12809 1/20 0.41
AKR1C3 P42330 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
DRD2 P14416 2/20 0.40
ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2750409 0.87 MAPT (0.50) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL1006036 0.79 LMNA (0.54) MAPTLMNACHRNA7SIGMAR1HTR3E
Hydrochloric Acid SCHEMBL14334304 0.77 LMNA (0.52) MAPTLMNACHRNA7SIGMAR1HTR3E
Bromide SCHEMBL19272502 0.77 LMNA (0.52) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL7678643 0.75 DRD4 (0.50) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL2046994 0.75 LMNA (0.50) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL164538 0.74 LMNA (0.67) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL385012 0.74
SCHEMBL576454 0.74 LMNA (0.67) MAPTLMNACHRNA7SIGMAR1HTR3E
SCHEMBL576814 0.74 LMNA (0.67) MAPTLMNACHRNA7SIGMAR1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761587-B1 PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER EVONIK ROEHM GMBH (DE) 2010-01-20 EP claimed
CN-101481488-A Method for preparing spray drying poly(methyl) acrylate polymer, and use of the polymer as polymer ingredient of plasticized sol ROEHM GMBH (DE) 2009-07-15 CN disclosed
CN-101481486-A Improved polymethacrylate plasticized sol ROEHM GMBH (DE) 2009-07-15 CN disclosed
CN-101481485-A Foamed poly (methyl) acrylic ester plasticized sol, as well as preparation, use and moulded product thereof ROEHM GMBH (DE) 2009-07-15 CN disclosed
US-6989409-B2 Method for synthesis of spray-dried poly(METH)acrylate polymers, use of same as polymer components for plastisols, and plastisols produced therewith ROEHM GMBH & CO. KG (DE) 2006-01-24 US disclosed
US-20040059023-A1 Method for synthesis of spray-dried poly(METH)acrylate polymers, use of same as polymer components for plastisols, and plastisols produced therewith ROEHM GMBH (DE) 2004-03-25 US disclosed
CN-1142213-C Improved poly(meth) acrylate plastisols and method for producing the same ������������� 2004-03-17 CN disclosed
US-6498209-B1 EMULSION POLYMERIZED HOMOPOLYMERS OR COPOLYMERS; SUPERIOR SHELF LIFE, TENSILE STRENGTH EXTENSIBILITY, VISCOSITY, GEL FORMATION AND FILM FORMING ROEHM GMBH & CO. KG (DE) 2002-12-24 US disclosed
CN-1327463-A Improved poly(meth) acrylate plastisols and method for producing the same RHOM GES MIT BESCHREKTER HAFTU (DE) 2001-12-19 CN disclosed
US-5744565-A SUSPENSION POLYMERIZING METHYL METHACRYLATE WITH OR WITHOUT OTHER MONOMERS IN PRESENCE OF DISPERSANT AND PROTECTIVE COLLOID IN WATER CONTAINING PEROXIDE INITIATORS, SEPARATING AND COMMNUATING THE BEADS ROEHM GMBH CHEMISCHE FABRIK (DE) 1998-04-28 US disclosed