Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 8/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852333 | 0.84 | DDX3X (0.50) | DDX3XNOTUMKCNH2P2RX7F9 | |
| SCHEMBL2854482 | 0.76 | DDX3X (0.49) | DDX3XNOTUMKCNH2F9 | |
| SCHEMBL2857939 | 0.74 | DDX3X (0.58) | DDX3XF9 | |
| SCHEMBL2855135 | 0.72 | DDX3X (0.47) | DDX3XNOTUMKCNH2CA1CA2 | |
| SCHEMBL2850881 | 0.71 | DDX3X (0.49) | DDX3XF9 | |
| SCHEMBL2855133 | 0.71 | F9 (0.47) | DDX3XNOTUMKCNH2F9 | |
| SCHEMBL2860025 | 0.71 | F9 (0.47) | DDX3XNOTUMKCNH2F9 | |
| SCHEMBL2852013 | 0.71 | MAPK13 (0.49) | DDX3XNOTUMKCNH2F9 | |
| SCHEMBL2854515 | 0.70 | DDX3X (0.46) | DDX3XNOTUMKCNH2F9 | |
| SCHEMBL2852561 | 0.70 | NOTUM (0.48) | DDX3XNOTUMKCNH2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | disclosed |