Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630795 | 0.85 | LMNA (0.77) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL20033137 | 0.85 | LMNA (0.77) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL3951779 | 0.83 | KDM4E (0.41) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL4029 | 0.82 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL3399 | 0.82 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL15479016 | 0.82 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL10867491 | 0.82 | LMNA (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL2636850 | 0.82 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL2961583 | 0.82 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL30850134 | 0.82 | LMNA (0.36) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259799-A1 | COMBINATION OF IMMUNOMODULATOR AND ANTI-PATHOGENIC AGENT | Nunes, Iseu Da Silva (BR) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009097670-A1 | COMBINATION OF IMMUNOMODULATOR AND ANTI-PATHOGENIC AGENT | NUNES ISEU DA SILVA (BR) | 2009-08-13 | — | — | WO | disclosed |